Systems and methods for safe medicament transport

摘要

A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

主权项

1. A process of operating an automation system for effectuating transport of a medicament, the process comprising the steps of:
attaching a vial adapter assembly to a preselected vial containing a quantity of a medicament into an automation system, the vial adapter assembly including a first seal and a second seal, and the vial being capped by a stopper; loading the preselected vial having the vial adapter assembly attached thereto into the automation system; loading syringes into the automation system; loading a plurality of syringe adapters into the automation system; performing a medicament extraction process, including the steps of:
selecting an appropriate syringe;connecting a syringe adapter assembly to the selected syringe;moving the selected syringe and syringe adapter assembly into connection with the loaded vial and vial adapter assembly, wherein a seal of the syringe adapter assembly makes connection with the first seal of the vial adapter assembly;advancing the syringe toward the loaded vial while the stopper of the loaded vial is in abutting engagement with the second seal of the vial adapter assembly;penetrating a transfer needle of the vial adapter assembly through the second seal of the vial adapter assembly and through the stopper of the vial,withdrawing a plunger of the syringe relative to a barrel of the syringe to begin withdrawing a fluid from the loaded vial;advancing the plunger relative to the barrel of the syringe to inject fluid back into the loaded vial; andwithdrawing the plunger relative to the barrel of the syringe to withdraw the fluid from the loaded vial to complete a transfer of a medicament from the loaded vial to the syringe; and disengaging the syringe from the vial adapter assembly.