| 摘要 |
A process is claimed for the enantioselective epoxidation of alpha,beta-unsaturated ketones, in which a compound of the general formula I, is reacted with an oxidizing agent to form alpha,beta-epoxy ketones of the general formula II, in which R1, R2, R3 are as defined above. The alpha,beta-epoxy ketones of the general formula II can be obtained in good yields and outstanding enantioselectivities from alpha,beta-unsaturated ketones of the general formula I by epoxidation with hydrogen peroxide in the presence of a chiral catalyst, such as amino compounds and their acid addition salts. |
