| 主权项 |
1. A compound of the formula (I) wherein
A is selected from the group consisting of
H and C1-6-alkyl; R1 and R2 are independently selected from the group consisting of
H, C1-6-alkyl and C3-6-cycloalkyl, wherein at least one of R1 or R2 is C1-6-alkyl or C3-6-cycloalkyl,wherein the C1-6-alkyl or the C3-6-cycloalkyl is optionally substituted with halogens or MeO—, orwherein R1 and R2 together form a 2- to 5-membered alkylene-bridge optionally substituted with halogens incorporating 0 to 2 heteroatoms independently selected from the group consisting of N, O and S;W is selected from the group consisting of a
mono- or bicyclic aryl, a mono- or bicyclic heteroaryl, a mono- or bicyclic heterocyclyl and a mono- or bicyclic cycloalkyl,
wherein each of these ring systems are optionally substituted with one or more R3, andwherein the heteroaryl comprises up to 4 heteroatoms and one or two 5- or 6-membered ring(s);R3 is independently selected from the group consisting of
C1-6-alkyl, C3-8-cycloalkyl, C1-6-alkyl-O—, benzyl, halogen, HO—, NC—, mono- or bicyclic heteroaryl, and 5- or 6-membered monocyclic heterocyclyl containing one heteroatom selected from the group consisting of N, O or S(O)r, wherein the heteroaryl contains up to 4 heteroatoms and one or two 5- or 6-membered rings(s) and r is 0, 1 or 2,
wherein the C1-6-alkyl, C3-8-cycloalkyl, C1-6-alkyl-O—, benzyl, heteroaryl and the heterocyclyl are optionally substituted with halogens, HO—, acetyl, C1-6-alkyl-O—, oxo, R4—S(O)2—, with R4 being aryl, C3-6-cycloalkyl and/or C1-6-alkyl; andY is selected from the group consisting of a bond, —CH2—, —CH2CH2—, and —OH2O—; or a salt thereof. |
