METHOD AND DEVICE FOR MEASURING HAEMOGLOBIN IN THE EYE

摘要

Based on the identification by colorimetry of a colour image of the fundus of the eye of an individual, obtained by specialised cameras (fundus camera or retinograph). The method and the device of the present invention enable establishing a direct relation between the chromatic properties of the various tissues of the optic nerve (10) and the amount of haemoglobin (Hb) in the optic nerve head (10), allowing identification and clearly distinguishing the irrigated regions of the optic nerve (10) from the non-irrigated regions or those with atrophy, constituting a tool of great interest in monitoring and diagnosis of glaucomatous disease and other optic diseases affecting vascularisation. This method also allows taking into account the effect of loss of transparency of the lens in patients with cataracts, as this effect is compensated without affecting the final results of the determination of the amount of haemoglobin (Hb).

主权项

1. Method of measuring haemoglobin (Hb) “ex vivo” of an individual characterised in that it comprises the following stages:
a) identification of the optic nerve head (10) using colorimetry of a colour image captured of the fundus of the eye, identifying the central vessels (11) of the retina of the optic nerve (10) and the tissue (12) of the eye that surrounds them; b) establishing of a first measurement, as a measurement of the amount of red light reflected (R) in the central vessels (11) of the retina on their passage through the optic nerve head (10), establishing this amount as the maximum reference value of haemoglobin (Hb); c) establishing a second measurement, as the measurement of the amount of red (R) reflected light in the tissue (12) of the eye itself; and d) comparing both measurements for the determination of the amount of haemoglobin (Hb) in the tissue (12) of the optic nerve head (10), this amount being obtained as a ratio of the second measurement compared to the first measurement.