| 发明名称 |
ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 |
| 摘要 |
<p>Antibodies which block the binding of human Programmed Death Receptor 1 (hPD-1) to its ligands (hPD-L1 or hPD-L2) and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune response through the PD-1 pathway is also disclosed.</p> |
| 申请公布号 |
KR20140133954(A) |
申请公布日期 |
2014.11.20 |
| 申请号 |
KR20147030247 |
申请日期 |
2008.06.13 |
| 申请人 |
MERCK SHARP & DOHME B.V. |
发明人 |
CARVEN GREGORY JOHN;VAN EENENNAAM HANS;DULOS GRADUS JOHANNES |
| 分类号 |
C07K16/00;A61K39/395;A61P35/00 |
主分类号 |
C07K16/00 |
| 代理机构 |
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