| 发明名称 |
USE OF CITRAL FOR TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS |
| 摘要 |
The present invention relates to a new use of citral for manufacturing a medicament for treating focal segmental glomerulosclerosis (FSGS). Particularly, the present invention discloses that citral is effective in alleviating symptoms of FSGS, including reducing glomerular epithelial hyperplasia lesions (EPHLs), peri-glomerular inflammation or glomerular hyalinosis or sclerosis, and also reducing proteinuria or hematuria or lowering serum urea nitrogen level or serum creatinine level in the subject. |
| 申请公布号 |
US2014343167(A1) |
申请公布日期 |
2014.11.20 |
| 申请号 |
US201414251426 |
申请日期 |
2014.04.11 |
| 申请人 |
National Defense Medical Center |
发明人 |
CHEN Ann;HUA Kuo-Feng;KA Shuk-Man;CHAO Kuo-Ping;CHANG Wen-Liang;HWA Kuo-Yuan |
| 分类号 |
A61K31/11;A61K45/06 |
主分类号 |
A61K31/11 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating focal segmental glomerulosclerosis (FSGS) in a subject in need thereof, which comprises administering a therapeutically effective amount of citral to the subject. |
| 地址 |
Taipei TW |
