发明名称 |
Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use |
摘要 |
Combinations of the antibody-drug conjugate trastuzumab-MCC-DM1 and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting tumor cell growth, and for treating disorders such as cancer mediated by HER2 and KDR (VEGFR receptor 1). Methods of using such combinations for |
申请公布号 |
AU2009225877(B2) |
申请公布日期 |
2014.11.20 |
申请号 |
AU20090225877 |
申请日期 |
2009.03.10 |
申请人 |
GENENTECH, INC. |
发明人 |
PHILLIPS, GAIL LEWIS;BERRY, LEANNE;SLIWKOWSKI, MARK X. |
分类号 |
A61K31/337;A61K31/416;A61K31/513;A61K31/517;A61K31/5355;A61K31/555;A61K39/395;A61K45/06;A61P35/00 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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