发明名称 |
POLYNUCLEATED MEGAKARYOCYTIC CELL AND METHOD FOR MANUFACTURING PLATELETS |
摘要 |
An object of the present invention is to provide a method of promoting polyploidization of megakaryocytes and thereby producing highly polyploidized megakaryocytes, a method of efficiently producing platelets from polyploidized megakaryocytes, and the like. The present invention provides a method of producing polyploidized megakaryocytes comprising a step of forcing expression of an apoptosis suppressor gene in megakaryocytes before polyploidization and culturing the resulting cells. |
申请公布号 |
EP2708597(A4) |
申请公布日期 |
2014.11.19 |
申请号 |
EP20120785650 |
申请日期 |
2012.05.11 |
申请人 |
THE UNIVERSITY OF TOKYO |
发明人 |
ETO, KOJI;NAKAUCHI, HIROMITSU;TAKAYAMA, NAOYA;NAKAMURA, SOU |
分类号 |
C12N5/10;A61K35/14;A61P7/00;C12N15/09 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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