发明名称 |
PROCESS FOR THE SYNTHESIS OF ETORICOXIB |
摘要 |
The present invention relates to a process for the synthesis of the anti-inflammatory agent 5-chloro-3-(4-methanesulfonylphenyl)-6′-methyl-[2,3′]bipyridine, referred to as compound of formula (1) or etoricoxib, which is a pharmaceutically active ingredient inhibiting cyclooxygenase-2. In particular, the application concerns a novel process of making the compound of formula (1) by oxidizing a compound of formula (4). |
申请公布号 |
EP2802564(A1) |
申请公布日期 |
2014.11.19 |
申请号 |
EP20130701362 |
申请日期 |
2013.01.11 |
申请人 |
ALFRED E. TIEFENBACHER (GMBH & CO. KG);SHANGHAI GOLDEN PHARMATECH CO., LTD. |
发明人 |
MAO, ZHENMIN;LAN, TIAN;LIU, LANFANG;YAN, LONG;BECKER, STEFAN |
分类号 |
C07D213/46;C07D213/61 |
主分类号 |
C07D213/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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