Luminescent conducting nano-drug crystal ultra-thin film self-assembly and uses

摘要

This invention involves two fields of photoelectron information materials and pharmaceuticals, especially refers to the self-assembly of conducting photoluminescence nanomedicine crystals and thin films and their preparation processes. In the invention, self-assembling unitary, binary, ternary and quaternary complexes of an antioxidase antioxidant, an agonist of the β-adrenergic receptors, an agonist of the P2-purinergic receptors and an antagonist of benzalkonium-typed calcium channels is to employ an interaction of inelastic electron tunneling, which possesses photoelectron properties of inelastic electron tunneling and photoluminescence with the central wavelength ˜500 nm and the wavelength wide ˜200 nm in the size-controlled square or cubic geometrical complexes. The invention is not only beneficial for drug discovery targeted disease mechanisms, but also profitable for inventions of photoelectron sensing new materials.

主权项

1. A low power three-dimensional (3D) self-assembled conducting photoluminescent nanomedicine, comprising:
3D unitary, binary, ternary, and quaternary nanomedicine crystals of isoprenaline, adenosine triphosphate, verapamil, and superoxide dismutase, in a L16(2)15 test protocol that includes four unitary groups, six binary groups, four ternary groups and one quaternary group at two levels of 0 and 1, and a L9(3)4 test protocol that includes nine quaternary groups at three levels of 1, 2 and 3, the 3D unitary, binary, ternary, and quaternary nanomedicine crystals disposed on a substrate of graphite and/or silicon, wherein the 3D unitary, binary, ternary, and quaternary nanomedicine crystals have a length from 400 nm to 1000 nm, a width from 400 nm to 1000 nm, and a height from 0.3 nm to 95 nm, and the low power three-dimensional (3D) self-assembled conducting photoluminescent nanomedicine has an inelastic electron tunneling property, a conducting property having a range of 1-8 μeV, and a photoluminescent property having a maximum photoluminescence intensity at 2000 absorbance units, a photoluminescence bandwidth covering 450-750 nm, and a central photoluminescence peak being located around 550 nm after subtraction of a background signal.