发明名称 |
METHOD FOR MAKING SOLID DISPERSIONS OF HIGHLY CRYSTALLINE THERAPEUTIC COMPOUNDS |
摘要 |
<p>A process for preparing solid dispersions of highly crystalline compounds. The highly crystalline or thermally labile therapeutic compounds are processed in an extruder in combination with a solubilizing agent and optionally a plasticizer. The resulting extrudate features the therapeutic compound in an amorphous state. Particularly useful as the solubilizing agents are surfactants such as poloxamers.</p> |
申请公布号 |
KR101462693(B1) |
申请公布日期 |
2014.11.17 |
申请号 |
KR20097005216 |
申请日期 |
2007.08.14 |
申请人 |
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发明人 |
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分类号 |
A61K9/14;A61K9/16;A61K47/34;A61P35/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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