COMPOSITIONS AND METHODS FOR PROGNOSIS AND TREATMENT OF PROSTATE CANCER

摘要

Described herein are compositions and methods for prognosis and treatment of prostate cancer patients. Specifically the invention relates to microRNA molecules associated with the prognosis of prostate cancer, as well as various nucleic acid molecules relating thereto or derived therefrom.

主权项

1. A method for determining a prognosis for prostate cancer in a subject comprising:
(a) providing a biological sample from the subject; (b) determining the expression level of a nucleic acid sequence selected from the group consisting of SEQ ID NOS: 1-91 and sequences at least about 80% identical thereto from said sample; and (c) comparing said expression level to a threshold expression level,
wherein the expression level of any of SEQ ID NOS: 1-91 and sequences at least about 80% identical thereto compared to said threshold expression level is indicative of the prognosis of said subject.