Disclosed is a human murine chimeric antibody which substantially retains the antigen binding region of its murine counterpart and displays improved binding affinities to the antigen and/or ore homogenous binding to target cells.
申请公布号
EP2801584(A1)
申请公布日期
2014.11.12
申请号
EP20140170861
申请日期
2008.12.23
申请人
BIOTEST AG
发明人
KRAUS, ELMAR;BRUECHER, CHRISTOPH;DAELKEN, BENJAMIN;GERMER, MATTHIAS;ZENG, STEFFEN;OSTERROTH, FRANK;UHEREK, CHRISTOPH;AIGNER, SILKE;SCHULZ, GREGOR