发明名称 |
Topical therapy for the treatment of migraines, muscle sprains, muscle spasms, spasticity and related conditions |
摘要 |
The invention is directed to topical formulations and methods of treating a migraines and/or cluster headaches, muscle sprains, muscle spasms, spasticity, tension headaches, tension related migraines and related conditions associated with muscle tension and pain with a therapeutically effective amount of an ergot alkaloid, skeletal muscle relaxant, serotonin agonist, combinations thereof, pharmaceutically acceptable salt thereof, prodrugs thereof or derivative thereof. |
申请公布号 |
US8883830(B2) |
申请公布日期 |
2014.11.11 |
申请号 |
US201213349849 |
申请日期 |
2012.01.13 |
申请人 |
Afgin Pharma LLC. |
发明人 |
Aung-Din Ronald |
分类号 |
A01N43/82;A61K31/41;A01N43/38;A61K31/405;A61K31/44;A01N43/42;A01N43/58;A01N43/60;A61K31/50;A61K31/495;A61K47/10;A61K47/14;A61K9/00;A61K31/445;A61K31/455;A61K31/48;A61K31/55;A61K45/06;A61K31/551;A61K47/24;A61K9/06;A61K47/44;A61K31/498 |
主分类号 |
A01N43/82 |
代理机构 |
Davidson, Davidson & Kappel, LLC |
代理人 |
Davidson, Davidson & Kappel, LLC |
主权项 |
1. A method of treating migraines and cluster headaches with a topical formulation comprising applying a unit dose of a therapeutically effective amount of the active agent tizanidine or a pharmaceutically acceptable salt thereof incorporated into an immediate release pharmaceutically acceptable topical carrier onto the skin of a human patient experiencing an acute condition selected from the group consisting of migraine and cluster headache, at the posterior cervical area in close proximity to the brain stem, such that the unit dose provides a therapeutic effect within about 15 to about 30 minutes after topical administration to the human patient. |
地址 |
Sarasota FL US |