发明名称 PHARMACEUTICAL COMBINATIONS CONTAINING PYRIDO[4,3-d]PYRIMIDINE DERIVATIVES AS HSP90 INHIBITOR AND HER2 INHIBITOR
摘要 FIELD: medicine.SUBSTANCE: invention represents a combination for treating breast cancer, containing the HSP90 inhibitor and HER2 inhibitor, wherein the HSP90 inhibitor represents ethylamide 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid or its pharmaceutically acceptable salt, as well as a method of treating breast cancer, which involves administering an effective amount of this combination in a patient in need thereof.EFFECT: combination possesses the higher effectiveness as compared to its individual ingredients.6 cl, 1 ex, 1 tbl, 1 dwg
申请公布号 RU2532375(C2) 申请公布日期 2014.11.10
申请号 RU20110126251 申请日期 2009.11.25
申请人 NOVARTIS AG 发明人 KARLOS GARSIJA-EHCHEVERRIJA;MIKAEHL' JENSEN
分类号 A61K31/422;A61K39/395;A61P35/00 主分类号 A61K31/422
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