Patent Foramen Ovale (PFO) Closure Device with Radial and Circumferential Support

摘要

The present invention provides a device for occluding an anatomical aperture, such as a septal defect or patent foramen ovale (PFO). The occluder includes two sides connected by an intermediate joint. Each of the sides includes at least one elongate element, which is arranged to form non-overlapping loops. Each loop has at least one radially-extending segment that is adjacent to a radially-extending segment of another loop. In at least some embodiments, at least one pair of adjacent radially-extending segments is connected. The loops of the device may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. In some embodiments, at least one of the sides includes a tissue scaffold. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture, thereby exerting a compressive force on the septal tissue that is distributed along both the outer periphery of the occluder and the radially-extending segments.

主权项

1. A method for occluding a defect in septal tissue, comprising: deploying an occluding device at a defect of the septal tissue, the occluding device comprising:
a first side adapted to be disposed on a distal side of septal tissue with a defect and a second side adapted to be disposed on a proximal side of the septal tissue with a defect, the first side and second side being connected by an intermediate joint; said first and second sides adapted to occlude the defect upon deployment of the device at a delivery location; and said first and second sides each comprising at least one wire arranged to form non-overlapping adjacent loops that are held together at the intermediate joint and extend radially from a center axis upon deployment of the device; wherein said loops of said first and second sides are adapted to exert a compressive force on opposing sides of the septal tissue to occlude the defect; and, wherein further the second side of the device further comprises a tip, and the wire of each loop of the second side extends radially outward from the tip, bends, and then extends back to the intermediate joint.