摘要 |
The present invention relates to compounds of formula (I): I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, W, Y, mand nare as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of a variety of diseases that are mediated or sustained by aldosterone activity, including renal disease, diabetic nephropathy, cardiovascular diseases and fibrotic disorders, processes for preparing these compounds and intermediates useful in these processes. |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;BALESTRA, MICHAEL;BURKE, JENNIFER;CHEN, ZHIDONG;COGAN, DEREK;FADER, LEE;GUO, XIN;MCKIBBEN, BRYAN;MARSHALL, DANIEL RICHARD;NEMOTO, PETER ALLEN;YU, HUI |
发明人 |
BALESTRA, MICHAEL;BURKE, JENNIFER;CHEN, ZHIDONG;COGAN, DEREK;FADER, LEE;GUO, XIN;MCKIBBEN, BRYAN;MARSHALL, DANIEL RICHARD;NEMOTO, PETER ALLEN;YU, HUI |