发明名称 (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE AND SALTS THEREOF
摘要 The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system.;In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I):;;wherein HA is a pharmaceutically acceptable acid and R1-R4 are each independently selected from the group consisting of hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, and di-C1-C6-alkylamino-C2-C6-alkoxy.;The invention also relates to the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.
申请公布号 US2014329826(A1) 申请公布日期 2014.11.06
申请号 US201414274131 申请日期 2014.05.09
申请人 Proximagen Limited 发明人 Fleck Tom;Cernerud Magnus;Lundstrom Helena;Lofstrom Claes;Pelcman Margit;Paptchikhine Alexander;Nylen Emma;Nygren Alf
分类号 C07D401/14 主分类号 C07D401/14
代理机构 代理人
主权项
地址 London GB