| 发明名称 |
SERINE/THREONINE KINASE INHIBITORS |
| 摘要 |
<p>Compounds having the formula I, or a pharmaceutically acceptable salt thereof, wherein R1, R2, X1, X2, and Ar are as defined herein, are inhibitors of PAKl. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.</p> |
| 申请公布号 |
WO2014179496(A1) |
申请公布日期 |
2014.11.06 |
| 申请号 |
WO2014US36246 |
申请日期 |
2014.04.30 |
| 申请人 |
AFRAXIS HOLDINGS, INC.;GENENTECH, INC. |
发明人 |
DURÓN, SERGIO;CAMPBELL, DAVID;NDUBAKU, CHUDI;RUDOLPH, JOACHIM |
| 分类号 |
C07D471/04;A61K31/4353;A61P29/00;A61P35/00 |
主分类号 |
C07D471/04 |
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