| 发明名称 |
BENZIMIDAZOLE DERIVATIVES AS SELECTIVE BLOCKERS OF PERSISTENT SODIUM CURRENT |
| 摘要 |
The present invention is directed to methods of treating diseases or conditions mediated by elevated persistent sodium channel, such as ocular disorders, pain, multiple sclerosis, and seizure disorders utilizing a compound of Formula I or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising said compound, wherein variables R, R1, R2, R3, R4, R5, m, and n in Formula I are as defined herein. |
| 申请公布号 |
EP2797896(A1) |
申请公布日期 |
2014.11.05 |
| 申请号 |
EP20120810523 |
申请日期 |
2012.12.27 |
| 申请人 |
ALLERGAN, INC. |
发明人 |
EHRING, GEORGE R.;GARST, MICHAEL E.;AVEY, JR., ALFRED A.;DOLBY, LLOYD J.;ESFANDIARI, SHERVIN;MACKENZIE, VIVIAN R.;MARSDEN, JEREMIAH A.;MUCHMORE, DAVID C. |
| 分类号 |
C07D235/14;A61K31/00;A61K31/4184;A61K31/454;A61K31/496;A61K31/5377;A61P25/00;A61P25/02;A61P25/08;A61P25/28;A61P27/00;A61P27/02;A61P29/00 |
主分类号 |
C07D235/14 |
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