发明名称 |
PROCESSO PARA A PREPARAÇÃO DE INTERMEDIÁRIO DE INIBIDOR DA PROTEASE DE HCV |
摘要 |
<p>The present invention relates to a new process for the preparation of tripeptides of formula I wherein R1 is an amino protecting group and X is a halogen atom and wherein the tipeptide contains two olefinic moieties suitably disposed to undergo an intramolecular olefin metathesis reaction and produce macrocyclic tripeptides useful for the manufacture of macrocyclic HCV protease inhibitors.</p> |
申请公布号 |
BRPI0810665(A2) |
申请公布日期 |
2014.11.04 |
申请号 |
BR2008PI10665 |
申请日期 |
2008.04.15 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
FRANCOIS GANTZ;HELMUT STAHR |
分类号 |
C07D403/12;C07D487/04 |
主分类号 |
C07D403/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|