发明名称 | Polymorph of rifaximin and process for the preparation thereof | ||
摘要 | The present invention relates to a new polymorph of Rifaximin, designated κ, and to a process for the preparation thereof. Under certain aspects, the invention also relates to pharmaceutical compositions comprising an effective amount of the polymorphic form κ of Rifaximin and a pharmaceutically acceptable carrier and its uses in the treatment of gastrointestinal conditions. | ||
申请公布号 | US8877770(B2) | 申请公布日期 | 2014.11.04 |
申请号 | US201214118740 | 申请日期 | 2012.05.18 |
申请人 | Clarochem Ireland Limited | 发明人 | Vigano' Enrico;Molteni Renato;Lanfranconi Simona;Arrighi Massimiliano;Gatti Fabio |
分类号 | A61K31/437;C07D498/22 | 主分类号 | A61K31/437 |
代理机构 | Silvia Salvadori, P.C. | 代理人 | Silvia Salvadori, P.C. |
主权项 | 1. A crystalline form κ of Rifaximin, characterized by a powder XRD spectrum with peaks at values of the angle 2θ of 5.3°, 6.8°, 7.8°, 8.5°, 9.3°, 10.1°, 10.3°, 12.1°, 12.7°, 13.4°, 13.7°, 14.6°, 15.3°, 15.8°, 16.4°, 16.9°, 17.7°, 18.0°, 18.8°, 19.2°, 19.7°, 20.3° and 22.1°. | ||
地址 | Dublin IE |