发明名称 Formulations for bovine granulocyte colony stimulating factor and variants thereof
摘要 Disclosed is the use of a bG-CSF-T133pAF-20K PEG, a citrate or succinate buffer, arginine, and optionally a counter ion for arginine in the manufacture of a medicament for treatment of a disorder modulated by bG-CSF, wherein the medicament is a stable aqueous formulation containing less than 0.001% of a surfactant. Also disclosed is a stable aqueous formulation comprising bG-CSF-T133pAF-20K PEG, a citrate or succinate buffer, arginine, and optionally a counter ion for arginine, wherein said formulation contains less than 0.001% of a surfactant.
申请公布号 NZ608164(A) 申请公布日期 2014.10.31
申请号 NZ20110608164 申请日期 2011.09.22
申请人 ELI LILLY AND COMPANY 发明人 DAVAGNINO JUAN;KHA CATHERINE NGAN;KLOTZ ALAN VOSKAMP
分类号 A61K38/19;A61K47/48;A61P29/00;C07K14/535 主分类号 A61K38/19
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