| 摘要 |
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date (10) International Publication Number 20 November 2008 (20.11.2008) PCT W O 2008/141275 Al (51) International Patent Classification: (74) Agents: BROOKS, William, L. et al.; Edwards Angell C12Q 1/68 (2006.01) Palmer & Dodge LLP, P.O. Box 55874, Boston, MA 02205 (US). (21) International Application Number: PCT/US2008/063408 (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (22) International Filing Date: 12 May 2008 (12.05.2008) AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CI, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, (25) Filing Language: English EG, ES, FI, GB, GD, GE, GI, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, (26) Publication Language: English LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, (30) Priority Data: PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, 60/928,813 11 May 2007 (11.05.2007) US SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, 60/994,416 19 September 2007 (19.09.2007) US ZA, ZM, ZW. 61/001,457 1 November 2007 (01.11.2007) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GI, (71) Applicant (for all designated States except US): THE GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, JOHNS HOPKINS UNIVERSITY [US/US]; 3400 N. ZW), Eurasian (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM), Charles Street, Baltimore, MD 21218 (US). European (AT, BE, BG, CI, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, IHU, IE, IS, IT, LT, LU, LV, MC, MT, NL, (72) Inventors; and NO, PL, PT, RO, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, (75) Inventors/Applicants (for US only): ALANI, Rhoda, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Myra [US/US]; 16 Hambleton Court, Baltimore, MD 21208 (US). BYUNGWOO, Ryu [US/US]; 5629 High Published: Tor Hill, Columbia, MD 21045 (US). KEEFE, Megan, J. - with international search report [-/US]; 1 Pinewall Place #2b, Nottingham, MD 21236 - with information concerning one or more priority claims (US). considered void (54) Title: BIOMARKERS FOR MELANOMA (57) Abstract: The present invention relates to methods of determining melanoma status in a subject. The invention also relates to kits for determining melanoma status in a subject. The invention further relates to methods of identifying biomarkers and correlating biomarker expression to melanoma status or stage in a subject. |
