| 发明名称 |
HYDROXYINDOLE CARBOXYLIC ACID BASED INHIBITORS FOR ONCOGENIC SRC HOMOLOGY-2 DOMAIN CONTAINING PROTEIN TYROSINE PHOSPHATASE-2 (SHP2) |
| 摘要 |
Inhibitors of protein tyrosine phosphatases are disclosed. The inhibitors include hydroxyindole carboxylic acids having a linker and an amine scaffold that are potent inhibitors of Src homology 2-domain containing protein tyrosine phosphatase-2. |
| 申请公布号 |
CA2944198(A1) |
申请公布日期 |
2014.10.30 |
| 申请号 |
CA20142944198 |
申请日期 |
2014.04.25 |
| 申请人 |
INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION |
发明人 |
ZHANG, ZHONG-YIN;ZENG, LI-FAN |
| 分类号 |
A61K31/405;A61K31/404;A61P35/00 |
主分类号 |
A61K31/405 |
| 代理机构 |
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