| 发明名称 |
PROTEOLYTICALLY RESISTANT HYDROGEN BOND SURROGATE HELICES |
| 摘要 |
<p>The present invention relates to peptidomimetics having a stable, internally constrained protein secondary structure, where the peptidomimetics contain a hydrogen bond surrogate in the internal constraint, and at least one beta amino acid. Methods for promoting cell death using peptidomimetics that inhibit p53/hDM2 are also disclosed.</p> |
| 申请公布号 |
EP2793920(A1) |
申请公布日期 |
2014.10.29 |
| 申请号 |
EP20120859663 |
申请日期 |
2012.12.21 |
| 申请人 |
NEW YORK UNIVERSITY |
发明人 |
ARORA, PARAMJIT, S.;PATGIRI, ANUPAM;JOY, STEPHEN |
| 分类号 |
A61K38/04;C07K1/107;C07K5/12 |
主分类号 |
A61K38/04 |
| 代理机构 |
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代理人 |
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