Medical devices and coatings therefore comprising biodegradable polymers with enhanced functionality

摘要

Biodegradable polymers useful for fabricating implantable medical devices and as coatings for medical devices are provided. The biodegradable polymers are biocompatible and can be tuned to provide optimum bioactive agent elution rates as well as degradation rates. Also provided are methods for making medical devices and medical device coatings using the biodegradable polymers.

主权项

1. An implantable medical device having a coating comprising: a biocompatible, biodegradable polymer of Formula I: wherein n and m are separately integers from 1 to 100, X is an integer from 0 to 20, R1 is hydrogen or a C1-C10 straight chain or branched alkyl or a C1-C10 straight chain or branched alkenyl and R2 is a functional group selected from the group consisting of oxo, hydroxyl, carboxylic acid, amino, vinyl, poly(ethylene glycol) and phosphoryl choline.