| 主权项 |
1. A compound of formula (I) in which R1/R2 are independently from each other hydrogen, halogen or phenyl-S—,
R3 is independently from each other hydrogen, 1-6C-alkoxy, halogen, 2-6C-alkenyl, 3-6C-cycloalkyl, 1-6C-haloalkoxy or C(O)OH, n is 1-3, R4 is
(a) hydrogen,(b) hydroxy,(c)1-6C-alkoxy opt. subst. with
(c1) 1-2 OH,(c2) NR9R10,(c3) 1-4C-alkyl-S—,(c4) 1-4C-alkyl-S(O)—,(c5) 1-4C-alkyl-S(O)2—,(c6) —S(O)2NR9R10,(d) whereby the * is the point of attachment,
(e) whereby the * is the point of attachment,
(f) cyano,(g) 1-4C-alkyl-S(O)2—, R5 is
(a) hydrogen,(b) 2-6C-hydroxyalkyl,(c) whereby the * is the point of attachment,
(d) —C(O)-(1-6C-alkyl),(e) —C(O)-(1-6C-alkylen)-O-(1-6C-alkyl),(f) —C(O)-(1-6C-alkylen)-O-(1-6C-alkylen)-O-(1-6C-alkyl), R6 is hydrogen, halogen, cyano, C(O)NR11R12, C(O)OR13 or C(O)NHOH, R7 is hydrogen, 1-6C-alkyl, 2-6C-alkenyl, 1-6C-alkoxy, 3-6C-cycloalkyl, or NR9R10, R8 is hydrogen or 1-6C-alkyl, m is 1-4, R9, R10 are independently from each other hydrogen or 1-6C-alkyl, R11, R12 are independently from each other hydrogen, 1-6C-alkyl, 2-6C-hydroxyalkyl or (1-4C-alkyl)-SO2-(1-4C-alkyl), R13 is hydrogen or 1-4C-alkyl, or an N-oxide, a salt, a tautomer or a stereoisomer of said compound, or a salt of said N-oxide, tautomer or stereoisomer. |
