发明名称 CAGED PLATINUM NANOCLUSTERS FOR ANTICANCER CHEMOTHERAPEUTICS
摘要 A caged platinum nanocluster complex is disclosed. The complex comprises (a) an amine-terminated dendrimer; and (b) a platinum nanocluster comprising platinum oxides, the platinum nanocluster being confined inside of the amine-terminated dendrimer. The complex exhibits cytotoxicity to cancer cells. A double-caged platinum nanocluster complex is also disclosed, which comprises polyethylene glycol (PEG) coated on the surface of a dendrimer caged platinum nanocluster complex. The double-caged caged platinum nanocluster complex comprises pH-sensitive bonds on the surface thereof. Also disclosed are methods of preparing and using the same.
申请公布号 WO2014130429(A3) 申请公布日期 2014.10.23
申请号 WO2014US16826 申请日期 2014.02.18
申请人 NATIONAL HEALTH RESEARCH INSTITUTES;LIN, WEN-JYE 发明人 LIN, SHU-YI
分类号 A61K9/16;A61K33/24 主分类号 A61K9/16
代理机构 代理人
主权项
地址
您可能感兴趣的专利