发明名称 |
NON-INVASIVE SENSING OF FREE METAL IONS USING ION CHEMICAL EXCHANGE SATURATION TRANSFER |
摘要 |
The invention features a novel non-invasive approach for imaging, detecting and/or sensing metal ions with improved sensitivity and specificity in a biological sample or tissue. In certain embodiments, the invention provides a MR contrast-based approach for imaging, detecting and/or sensing metal ions in the biological sample/tissue containing various background ions by using 19F-based chemical exchange saturation transfer (CEST) technique. |
申请公布号 |
WO2014172651(A1) |
申请公布日期 |
2014.10.23 |
申请号 |
WO2014US34671 |
申请日期 |
2014.04.18 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
BAR-SHIR, AMNON;BULTE, JEFF;MC MAHON, MICHAEL, T. |
分类号 |
A61B5/055;A61K49/10;G01N24/10 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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