1,3,5 -TRIAZINE-2-AMINE DERIVATIVES, PREPARATION THEREOF AND DIAGNOSTIC AND THERAPEUTIC USE THEREOF

摘要

The present invention relates to compounds corresponding to formula (I) in which:—R1 represents a substituted phenyl;—R2 represents:—a substituted phenyl;—a heteroaromatic group, the said group being unsubstituted or substituted one or more times;—R3 represents a group Alk;—R4 represents a hydrogen atom or a (C1-C4)alkyl;—R5 represents a hydrogen atom, a (C3-C6)cycloalkyl or a (C1-C4)alkyl-O-Alk;—or alternatively R4 and R5, together with the nitrogen atom to which they are attached, constitute a heterocyclic radical chosen from: azetidin-1-yl, pyrrolidin-1-yl, piperid-1-yl, morpholin-4-yl;—R6 represents a group—COOAlk, a group—CONH2 or a group—NHSO2Alk;—Alk represents a (C1-C4)alkyl, which is unsubstituted or substituted one or more times with a halogen atom; in the form of the base or of an acid-addition salt. Preparation process and diagnostic and therapeutic use.