发明名称 |
ANTIANGIOGENIC BRASSINOSTEROID COMPOUNDS |
摘要 |
A method of treating a solid tumor in a mammal by inhibiting angiogenesis, including administering to the mammal which has a solid tumor selected from the group consisting of breast carcinoma, lung carcinoma, prostate carcinoma, colon carcinoma, ovarian carcinoma, neuroblastoma, central nervous system tumor, multiform glioblastoma and melanoma; a composition including brassinosteroids of general formula (I) wherein can be a single or double bond and the configurations of carbon atoms C22 and C23 respectively linked to the substituents HO are S for both carbon atoms and a pharmaceutically acceptable additive. |
申请公布号 |
EP2790707(A1) |
申请公布日期 |
2014.10.22 |
申请号 |
EP20120819024 |
申请日期 |
2012.12.14 |
申请人 |
CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS YTECNICAS (CONICET);INIS BIOTECH LLC |
发明人 |
RAMIREZ, JAVIER, ALBERTO;MICHELINI, FLAVIA, MARIANA;GALAGOVSKY, LYDIA, RAQUEL;BERRA, ALEJANDRO;ALCHE, LAURA, EDITH |
分类号 |
A61K31/575;A61K45/06;A61P35/00 |
主分类号 |
A61K31/575 |
代理机构 |
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代理人 |
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地址 |
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