Particle switching systems and methods using acoustic radiation pressure

摘要

The present invention comprises methods and systems that use acoustic radiation pressure.

主权项

1. A method for acoustically manipulating a particle using radial acoustic focusing comprising:
introducing into a channel a first fluid having a first acoustic contrast with a population of particles suspended therein; introducing into the channel a second fluid having a second acoustic contrast that is greater than the first acoustic contrast of the first fluid; flowing the first and second fluid in the channel; applying a radial acoustic radiation pressure to the channel; and acoustically focusing at least a portion of the population of particles from the first fluid to the second fluid, wherein the portion of the population of particles are acoustically focused relative to the first acoustic contrast of the first fluid and the second acoustic contrast of the second fluid, and wherein the portion of the population of particles in the second fluid is acoustically focused into a single file line to pass through an interrogation zone.