GLUCAGON-LIKE PEPTIDE-1 ANALOGUES AND USING THEM

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to a glucagon-like peptide-1 (GLP-1) analogues presented by general formula Iwherein X represents glycine or glycinamide. The GLP-1 analogue is resistant to the action of dipeptidyl-peptidase IV and thereby has the prolonged half-life in vivo. What is also presented is using the GLP-1 for reducing blood sugar.EFFECT: preparing the glucagon-like peptide-1.9 cl, 3 ex, 3 dwg, 1 tbl