PIPERAZINE DERIVATIVES

摘要

Disclosed are piperazine derivatives having the general formula: (I) Also disclosed are methods of treating a subject having cancer with this compound or a pharmaceutical composition comprising the compound.;

主权项

1. A compound having the general formula (I): where n is selected from the group consisting of 0, 1 and 2; X is CH or N; R1 is selected from the group consisting of hydrogen, alkyl, halogen, ether, cyano, pyridyl, COCR3, CO2R4, CONH2, NO2, and CF; R2 represents one or more substituents selected from the group consisting of hydrogen, halogen, alkyl, pyridyl, cyano, acetyl, phenyl and phenyl substituted with alkyl; R3 is selected from the group consisting of hydrogen, alkyl and CONH2; and R4 is alkyl.