发明名称 |
MicroRNA compounds and methods for modulating miR-21 activity |
摘要 |
Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-21, and also to treat diseases associated with abnormal expression of miR-21, such as fibrosis and cancer. |
申请公布号 |
AU2013251696(A1) |
申请公布日期 |
2014.10.16 |
申请号 |
AU20130251696 |
申请日期 |
2013.04.24 |
申请人 |
REGULUS THERAPEUTICS INC. |
发明人 |
BHAT, BALKRISHEN;MARCUSSON, ERIC |
分类号 |
C12N15/113;A61K31/712;A61P13/12;A61P35/00;A61P43/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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