摘要 |
The instant invention provides compounds of formula I which are JAK3 inhibitors. Specifically, the compounds of formula I are pyrrolo[2,3-d]pyrimidine derivative compounds. The instant invention also provides methods of treating JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer, by administering the pyrrolo[2,3-d]pyrimidine-derivative compounds of formula I. |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
AHEARN, SEAN, P.;CHRISTOPHER, MATTHEW;JUNG, JOON;PU, QINGLIN;RIVKIN, ALEXEY;SCOTT, MARK, E.;WITTER, DAVID, J.;WOO, HYUN CHONG;CASH, BRANDON;DINSMORE, CHRISTOPHER;GUERIN, DAVID |