主权项 |
1. A compound represented by Formula I, its individual enantiomers, individual diastereoisomers, individual tautomers or a pharmaceutically acceptable salt thereof wherein: R1 is substituted or unsubstituted C6-10 aryl, substituted or unsubstituted heterocycle, substituted or unsubstituted C5-8 cycloalkyl, substituted or unsubstituted C5-8 cycloalkenyl or hydrogen; R2 is hydrogen; R3 is hydrogen, halogen, substituted or unsubstituted C1-3 alkyl, C(O)R7 or hydroxyl; R4 is hydrogen, halogen, substituted or unsubstituted C1-3 alkyl, C(O)R7 or hydroxyl; R5 is hydrogen, halogen, substituted or unsubstituted C1-3 alkyl, C(O)R7, hydroxyl or substituted or unsubstituted heterocycle; R6 is hydrogen, halogen, substituted or unsubstituted C1-3 alkyl, C(O)R7, hydroxyl or substituted or unsubstituted heterocycle; R7 is hydrogen, —OR8 or substituted or unsubstituted C1-3 alkyl; R8 is H or C1-3 alkyl; a is 2 or 3; b is 1, 2 or 3; and c is 1, 2, 3, 4, 5 or 6. |