Analyte sensor

摘要

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

主权项

1. A method for measuring an analyte in a host, comprising:
exposing a continuous analyte detection system to a sample, wherein the continuous analyte detection system comprises a continuous analyte sensor configured for contact with a sample from a circulatory system of a host in vivo; and a reference sensor; generating a first signal of a glucose oxidase catalyzed reaction product with glucose; and a second signal associated with a glucose reference analyte; generating a non-glucose reference signal from the reference sensor; receiving in a processor module the first signal, the second signal, and the reference signal; calculating, using the processor module, a calibration factor based on the second signal and the reference signal, the calculated calibration factor providing a sensitivity of the continuous analyte sensor; and calibrating the first signal using the calibration factor.