| 发明名称 |
AGENT POSSESSING ANTI-INFLAMMATORY AND ANTIFIBROTIC ACTION IN PULMONARY TISSUE, AND CYTOSTATIC ACTION |
| 摘要 |
FIELD: medicine.SUBSTANCE: what is presented is using neuroleptic spiperone as an agent able to prevent developing disorders in pulmonary tissue caused by cytostatic bleomycin administered.EFFECT: anti-inflammatory and antifibrotic action of spiperone is presented on simulated reversible and irreversible pulmonary fibrosis caused by bleomycin with reducing a degree of alveocyte desquamation and delaying pulmonary tissue destruction.2 dwg, 3 tbl |
| 申请公布号 |
RU2530651(C1) |
申请公布日期 |
2014.10.10 |
| 申请号 |
RU20130149751 |
申请日期 |
2013.11.06 |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT FARMAKOLOGII" SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK |
发明人 |
DYGAJ ALEKSANDR MIKHAJLOVICH;SKURIKHIN EVGENIJ GERMANOVICH;PERSHINA OL'GA VIKTOROVNA;REZTSOVA ALENA MIKHAJLOVNA;ERMAKOVA NATALIJA NIKOLAEVNA;KRUPIN VJACHESLAV ANDREEVICH;KHMELEVSKAJA EKATERINA SERGEEVNA |
| 分类号 |
A61K31/438;A61K31/4166;A61P11/00;A61P35/00 |
主分类号 |
A61K31/438 |
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