| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to compounds of formula (I),in which Rstands for a phenyl group, optionally substituted with one or several halogen atoms; Rstands for hydrogen or a halogen atom or a cyanogroup; group -C(=O)Y, in which Y stands for a hydrogen atom or the group -NHor -OR; group -C(=S)NH; group -C(=NH)NH-OH; group -CHOH or -CHF; group -CH=N-OH; group -CH=CHor -C?C-R; group (II) or (III); and Rstands for the hydrogen atom or the (C-C)alkyl group; Rstands for thehydrogen atom or the (C-C)alkyl group; and Rstands for -NH, (C-C)alkyl, (C-C)fluoroalkyl or (C-C)cycloalkyl group. The invention also relates to methods of obtaining compounds of formula (I), a medical preparation, a pharmaceutical composition, intermediate compounds for obtaining the formula (I) compound and the application of the formula (I) compound and intermediate compounds.EFFECT: claimed compounds have anti-cancer activity.21 cl, 1 tbl, 28 ex |
