| 发明名称 |
PHARMACEUTICAL COMPOSITIONS COMPRISING NITROXYL DONORS |
| 摘要 |
The present disclosure provides nitroxyl donating pharmaceutical compositions comprising N-substituted hydroxylamine derivatives. The compositions are highly efficacious in treating cardiovascular diseases (e.g., heart failure), have a suitable toxicological profile, and are sufficiently stable for intravenous or oral administration. |
| 申请公布号 |
WO2014113700(A9) |
申请公布日期 |
2014.10.09 |
| 申请号 |
WO2014US12089 |
申请日期 |
2014.01.17 |
| 申请人 |
CARDIOXYL PHARMACEUTICALS, INC. |
发明人 |
KALISH, VINCENT JACOB;REARDON, JOHN;BROOKFIELD, FREDERICK ARTHUR;COURTNEY, STEPHEN MARTIN;FROST, LISA MARIE |
| 分类号 |
A61K31/18;A61P9/04;C07C317/14;C07D307/64 |
主分类号 |
A61K31/18 |
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