Compositions and Methods For Inhibiting Immunodeficiency Virus Transcription

摘要

The present disclosure provides methods of reducing immunodeficiency virus transcription, involving use of diflunisal or an active ester thereof. The disclosure also provides methods of treating an immunodeficiency virus infection in an individual, the method generally involving administering to the individual an effective amount of diflunisal or an active ester thereof.

主权项

1. A method of inhibiting enzymatic activity of a p300 acetyltransferase, the method comprising contacting the p300 acetyltransferase with a compound of the formula: or a physiologically active ester thereof.