| 发明名称 |
TARGETING MICRORNAS MIR-409-5P, MIR-379 AND MIR-154* TO TREAT PROSTATE CANCER BONE METASTASIS AND DRUG RESISTANT LUNG CANCER |
| 摘要 |
<p>The present invention describes methods of treating cancer, cancer metastasis, and drug resistant cancers using miRNA inhibitors; for example, inhibitors of miR-409-5p. Also described are methods of using the miRNA as biomarkers; for example, to predict responsiveness to a cancer drug, to detect a disease state of cancer.</p> |
| 申请公布号 |
EP2785355(A1) |
申请公布日期 |
2014.10.08 |
| 申请号 |
EP20120854115 |
申请日期 |
2012.11.30 |
| 申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
CHUNG, LELAND, W. K.;JOSSON, SAJNI;GURURAJAN, MURALI;JAIN, ANJALI |
| 分类号 |
A61K31/7088;A61K31/7105;A61K31/713;A61P35/00;C12N15/113;C12Q1/68;G01N33/50 |
主分类号 |
A61K31/7088 |
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