发明名称 AMINO ACID PREPARATION METHOD COMPRISING A STEP OF HYDROFORMYLATION OF AN UNSATURATED FATTY NITRILE
摘要 A method for synthesizing a ω-amino acid compound having formula HOOC—R′—CH2NH2, where R is an alkyl radical including between 6 and 15 carbon atoms or an alkylene radical including between 6 and 15 carbon atoms and between 0 and 2 unsaturations. The method including the following steps: 1) hydroformylation of an unsaturated fatty nitrile selected from compounds having formula R1—CH═CH—[(CH2)q—CH═CH]m—(CH2)r—CN, said step consisting in reacting the nitrile with the carbon monoxide and dihydrogen such as to obtain at least one fatty nitrile aldehyde having formula HOC—R′—CN; 2) dioxygen oxidation, wherein the nitrile aldehyde obtained in step 1) is converted into fatty nitrile acid having formula HOOC—R′—CN; and 3) reduction, in which the nitrile acid obtained in step 2) is converted into co-amino acid having formula HOOC—R′—CH2NH2.
申请公布号 EP2785682(A1) 申请公布日期 2014.10.08
申请号 EP20120810327 申请日期 2012.12.03
申请人 ARKEMA FRANCE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITÉ DE RENNES 1 发明人 DUBOIS, JEAN-LUC;COUTURIER, JEAN-LUC;CARPENTIER, JEAN-FRANÇOIS;TERNEL, JÉRÉMY
分类号 C07C227/04;C07C229/08;C07C253/30;C07C255/19 主分类号 C07C227/04
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