Neural stimulation devices and systems for treatment of chronic inflammation

摘要

A system for treating chronic inflammation may include an implantable microstimulator, a wearable charger, and optionally an external controller. The implantable microstimulator may be implemented as a leadless neurostimulator implantable in communication with a cervical region of a vagus nerve. The microstimulator can address several types of stimulation including regular dose delivery. The wearable charger may be worn around the subject's neck to rapidly (<10 minutes per week) charge an implanted microstimulator. The external controller may be configured as a prescription pad that controls the dosing and activity of the microstimulator.

主权项

1. A system for treating chronic inflammation in a patient, the system comprising:
an implantable microstimulator configured for implantation around a cervical portion of a vagus nerve to modulate inflammation by applying a low duty-cycle stimulation; a charger configured to be worn around the patient's neck and to charge the implantable microstimulator, the charger comprising an energizer coil configured to fit around the patient's neck, the charger having an open configuration and a closed configuration, wherein in the open configuration the charger is configured to be placed around the patients neck and the energizer coil is an open circuit, wherein in the closed configuration the charger is configured to be secured around the patient's neck and the energizer coil is a closed circuit that forms a solenoid loop around the patient's neck; and an external controller configured to set a dose amplitude and dose interval for the microstimulator.