| 发明名称 | Antibodies against and methods for producing vaccines for respiratory syncytial virus | ||
| 摘要 | The present invention relates to novel respiratory syncytial virus (RSV) F peptides and compositions comprising them. The present invention also relates to methods of evaluating anti-RSV antibody binding to F peptides. The present invention also relates to antibodies that immunospecifically bind to an F peptide of the present invention. The invention further provides methods and protocols for the administration of F peptides and/or antibodies that immunospecifically bind to F peptides for the prevention, neutralization, treatment of RSV infection. Additionally, the methods of the invention may be useful for the treatment, prevention and the amelioration of symptoms associated with RSV infection. | ||
| 申请公布号 | US8852608(B2) | 申请公布日期 | 2014.10.07 |
| 申请号 | US200913147051 | 申请日期 | 2009.12.23 |
| 申请人 | MedImmune, LLC | 发明人 | McAuliffe Josephine;Palmer-Hill Frances;Zhu Qing;Suzich Joann |
| 分类号 | A61K39/155;A61K39/42;C07K14/005;C12N7/00;C12N7/08;A61K39/00 | 主分类号 | A61K39/155 |
| 代理机构 | Mueting, Raasch & Gebhardt, P.A. | 代理人 | Mueting, Raasch & Gebhardt, P.A. |
| 主权项 | 1. An isolated respiratory syncytial virus (RSV) F peptide comprising the amino acid sequence of LSLINDMPITLDQKILMSS (SEQ ID NO:39) or LSLINDMPITNDQKILMSS (SEQ ID NO:40). | ||
| 地址 | Gaithersburg MD US | ||