| 发明名称 | Crystalline forms of zofenopril calcium | ||
| 摘要 | The present invention relates to two novel crystalline forms of zofenopril calcium, to processes for their preparation and their use in pharmaceutical compositions. | ||
| 申请公布号 | US8853421(B2) | 申请公布日期 | 2014.10.07 |
| 申请号 | US201213712409 | 申请日期 | 2012.12.12 |
| 申请人 | Generics [UK] Limited | 发明人 | Gore Vinayak Govind;Vijayakar Priyesh;Pehere Ashok |
| 分类号 | C07D207/00;C07D207/16 | 主分类号 | C07D207/00 |
| 代理机构 | Fulbright & Jaworski, LLP | 代理人 | Fulbright & Jaworski, LLP ;Rothenberger Scott D. |
| 主权项 | 1. A process for preparing zofenopril calcium, comprising the steps of: (a) dissolving a salt of zofenopril in a water miscible organic solvent; (b) mixing the solution obtained in step (a) with an aqueous solution of a calcium salt; and (c) isolating the zofenopril calcium with the proviso that the salt of zofenopril in step (a) is not an amine salt. | ||
| 地址 | Hertfordshire GB | ||