IMPLANTABLE SCAFFOLDS AND METHODS OF USE

摘要

Inventive concepts relate general to the field of implantable three-dimensional scaffolds. More particularly, methods of preparing and using implantable nanofibrous tissue scaffolds are described. Inventive scaffolds can be used for treatment of defects in a living organism, such as hard or soft tissue defects including bone.

主权项

1. A method of producing a nanofibrous tissue scaffold comprising steps of:
(a) generating biodegradable, synthetic nanofibers; (b) processing the nanofibers to generate nanofiber fragments; (c) combining a void forming material with the nanofiber fragments; (d) compressing the nanofiber fragments; and (e) heating the nanofiber fragments to generate a porous nanofibrous tissue scaffold.