Preparation of Regenerative Tissue Scaffolds

摘要

Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response.

主权项

1. A method for making a tissue scaffold, comprising:
dissolving a polymer in a solvent to make a solution; mixing the solution with a particulate acellular tissue matrix (ATM) to create a mixture; placing the mixture in a mold; and drying the mixture to form a tissue scaffold with a stable three-dimensional shape, wherein the tissue scaffold has a reduced immunological or inflammatory response when implanted in a human than the polymer alone.